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Pharmaceutical-Grade Methylene Blue

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Energize your mitochondria — one drop at a time.

Before Methylene Blue – mitochondrial cell energy
Before Methylene Blue
After Methylene Blue – enhanced cellular energy
After Methylene Blue
The science

How methylene blue supports cellular energy

Your cells run on ATP, the energy molecule made inside your mitochondria. Here is where methylene blue fits in.

  1. 1

    Enters the mitochondria

    At low doses, methylene blue crosses into the mitochondria, the structures inside your cells that turn oxygen and nutrients into energy.

  2. 2

    Shuttles electrons

    It can accept electrons and hand them on, helping keep the electron transport chain moving toward cytochrome c oxidase (Complex IV).

  3. 3

    Supports cellular energy

    Researchers link this redox cycling to higher oxygen use and ATP production. Much of this evidence comes from cell and animal studies, and human research is still early.

Source: Rodriguez P, et al. Multimodal randomized functional MR imaging of the effects of methylene blue in the human brain. Radiology. 2016. PMC5084971

Read the full explainer

Illustration: methylene blue shuttling electrons along the mitochondrial electron transport chain toward ATP production NADH MB Cyt c IV ATP +ATP +ATP +ATP Inner mitochondrial membrane Electron flow →

Dosage Calculator

Enter your weight to see what the commonly cited research ranges work out to in mg, mL and drops.

Research range mg mL Drops

Assumes 10 mg/mL (1% solution) and ~20 drops/mL. Reference only — not a dosing recommendation, and not medical advice.

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Before using this: methylene blue is a monoamine oxidase inhibitor and interacts dangerously with SSRI/SNRI antidepressants and other serotonergic medication. It is unsuitable for people with G6PD deficiency. Read the safety overview and speak with a healthcare professional first.